Hemorrhagic Fever with Renal Syndrome (Hantaviruses)

Hemorrhagic fever with renal syndrome (Hantaviruses)

Hantaviruses are enveloped RNA viruses belonging to the genus Hantavirus, family Bunyaviridae. These agents are usual parasites of wild rodents and insectivores. Many species worldwide are infected with these viruses and each Hantavirus type is carried by its own type specific rodent species. Human transmission occurs accidentally by inhalation of aerosolized virus containing particles, contact...

[Hemorrhagic fever with renal syndrome (Korean hemorrhagic fever)].

Characterization of Hemorrhagic Fever with Renal Syndrome Caused by Hantaviruses, Estonia

Thirty cases of hemorrhagic fever with renal syndrome (HFRS) due to Puumala virus (PUUV), Saaremaa virus (SAAV), and Dobrava virus infection were confirmed in Estonia. Except for the levels of serum creatinine, no remarkable differences were found in the clinical course of HFRS caused by PUUV and SAAV.

Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by beta3 integrins.

Hantaviruses replicate primarily in the vascular endothelium and cause two human diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). In this report, we demonstrate that the cellular entry of HFRS-associated hantaviruses is facilitated by specific integrins expressed on platelets, endothelial cells, and macrophages. Infection of human umbilical vein en...

Cellular Entry of Hantaviruses Which Cause Hemorrhagic Fever with Renal Syndrome Is Mediated by b3 Integrins

Cellular Entry of Hantaviruses Which Cause Hemorrhagic Fever with Renal Syndrome Is Mediated by b3 Integrins IRINA N. GAVRILOVSKAYA, ERIC J. BROWN, MARK H. GINSBERG, AND ERICH R. MACKOW* Department of Medicine and Department of Molecular Genetics and Microbiology, State University of New York at Stony Brook, Stony Brook, New York 11794; Washington University School of Medicine, St. Louis Missou...